Nataly Smith
FIG. 00 · Portrait, Austin

01 · Intro

Hi, I'm Nataly Smith.

Software at the intersection of AI, systems, and science.

Senior Software Engineer specializing in full-stack app development, with expertise in cloud technologies, mathematical modeling, and pipeline architecture.

Austin, Texas · Yale Alumni

02 · About

About

Senior Software Engineer who specializes in full-stack app development, with expertise in cloud technologies/infrastructure, mathematical modeling, and pipeline architecture.

I blend cutting-edge technology with mathematical rigor to solve complex problems across multiple domains. From implementing DeepMind's AlphaTensor algorithm in LAPACK to building privacy-first genomic platforms, my work spans the intersection of AI, scientific computing, and real-world applications.

I work mostly on AI these days, but I have a habit of exploring problems with deep rabbit holes—genomics, numerical computing, games, and whatever else seems worth building.

Rangen = 6
  1. 01

    AI platform

    Function Health

  2. 02

    Scientific computing

    LAPACK, HIV models

  3. 03

    Cloud systems

    Azure, AWS, GCP

  4. 04

    Genomics

    GeneKnow, Bruker

  5. 05

    Medtech

    SYMon, fracture set

  6. 06

    Full-stack

    Web, mobile, desktop

FIG. 01 · Working range

03 · Skills

Skills

Python and C# most often, then Bash, Lisp, Fortran, and whatever else a given project needs.

Languages

Python · R · C# · C · C++ · TypeScript · JavaScript · Dart · Fortran · GDScript · VB · Bash · MATLAB · HTML · CSS · SQL · Racket · Lisp

Frameworks & Libraries

React · Next.js · Tauri · Flutter · Electron · .NET · WPF/XAML · Scikit · OpenCV · Flask · LangGraph · NextFlow · Luigi

Tools & Platforms

Docker · Git · Firebase · Godot · PostgreSQL · IIS · Visual Studio · VS Code · Vim · Linux · Google Cloud Platform · Azure · AWS · JIRA · GitHub · Bitbucket

AI & Scientific Computing

Machine Learning · AI/ML · LangGraph · GPU Optimization · Scientific Computing · Linear Algebra · Performance Optimization · Mathematical Modeling · Computational Biology

Application Development

Full-Stack Development · Mobile App Development · Desktop Applications · Game Development · Cross-Platform · Real-time Systems · Privacy-First Design · Genomics Applications

Software Engineering

OOP · SOLID · Agile Development · Unit Testing · Integration Testing · Real-time Collaboration · Pipeline Architecture · Cloud Infrastructure · Multiplayer Systems

04 · Experience

Experience

Function Health. Gauntlet AI Fellow. Previously Bruker Cellular Analysis, McMaster-Carr, SYMon Holdings, and research at Yale.

  1. 01 · August 2025 - Present

    Senior Software Engineer, AI Platform

    Function Health · Austin, TX

    Lead engineer on new AI platform projects. Currently using AI to build AI systems, integrating LLMs and agentic workflows into production applications.

    • Lead engineer on new AI platform initiatives
    • LLM-based agentic workflows for productivity and efficiency
    • Development of customer-facing applications that leverage LLMs and agentic workflows
  2. 02 · June 2025 - August 2025

    Fellowship: Cohort II AI Challenger

    Gauntlet AI · Austin, TX

    Senior software engineer and second cohort member in a highly selective AI training fellowship program.

    • Built and integrated LLMs and agentic workflows into modern applications
    • Collaborated with top-tier engineers on AI-first projects and AI-assisted research
    • Specialized in advanced AI-first development of enterprise-grade applications
  3. 03 · January 2023 - June 2025

    Senior Software Developer

    Bruker Cellular Analysis · Remote

    Led development of cloud-native applications, infrastructure automation, and genomic sequencing systems.

    • Completed a full-scale Azure DevOps migration in 3 months by coordinating team efforts, automating migration processes, and creating custom programmatic tools
    • Increased critical application performance by 400% by leading a re-architecture of existing code
    • Expedited application runtime by 75% in another project, hitting product specifications with an on-time release
    • Built critical testing functionality ahead of schedule, expediting product release by 2 weeks
    • Enriched deployment life cycle and scalability through Docker and CI/CD orchestration
    • Constructed a multi-cloud implementation of genomic sequencing testing infrastructure
  4. 04 · January 2022 - January 2023

    Software Developer

    Bruker Cellular Analysis · Remote

    Main developer creating research tools for next-generation sequencing and genomic analysis.

    • Independently developed a web portal that enabled interdepartmental teams to access research tools
    • Introduced automated unit testing and integration testing into development packages
    • Worked with C++ computer vision libraries to improve sequencing technologies
  5. 05 · September 2021 - January 2022

    Computer Systems Engineer

    McMaster-Carr · Elmhurst, IL

    Systems engineer specializing in web development for business-critical applications.

    • Improved company knowledge sharing by creating an internal communications hub
    • Worked with an established SDLC involving cross-team coordination, testing, and release schedules
    • Delivered website features end to end: database schemas, business logic, REST APIs, and front-end
    • Interfaced with legacy systems for modern business-critical applications
  6. 06 · January 2021 - January 2024

    Co-Founder

    SYMon Holdings, LLC · United States

    Medical technology startup developing wearable technology for continuous analyte monitoring in humans, with a primary application in preventing chronic emergency admissions in dialysis patients. Funded with an initial seed grant of $1500.

    • Co-founded a medtech startup focused on continuous analyte monitoring
    • Directed product vision toward reducing emergency admissions for dialysis patients
  7. 07 · January 2020 - May 2021

    Directed Research: Miller-Jensen Laboratory

    Yale University · New Haven, CT

    Directed research building predictive models for the activation of latent HIV, specializing in computational analysis of phenotype states and gene expression.

    • Computational modeling of phenotype states using Network-Free Stochastic Simulator, NFsim
    • R and MATLAB programming to analyze HIV expression data
    • Generation of a parameter-phenotype interactome network
    • Visualization of data trends in latent HIV mathematical models
    • Published research findings in a peer-reviewed computational biology journal
  8. 08 · May 2019 - August 2019

    Directed Research

    Oden Institute for Computational Engineering and Sciences · Austin, TX

    Research focused on analyzing highly expressed proteins in cancer, combining molecular and statistical exploration of gene expression pathways.

    • Visualized protein-protein interactions using R, ChimeraX, and bioinformatic tools
    • Generated and explored 3D models of protein interfaces
    • Used TCGA high-throughput human data for gene enrichment analyses
    • Compared interfacial amino acid residue frequencies with structural protein data
    • Applied linear regression, frequency calculations, and original random models to gene expression data

Education · Honors

Education

Yale University

Bachelor of Science, Biomedical Engineering

Biocomputation · 2017 – 2021 · New Haven, CT

GPA 3.64 · Cum Laude

Languages: English (native), Spanish (native), French (professional)

Key courses
  • Data Structures
  • Data Science
  • Analysis of Algorithms
  • Biomedical Imaging
  • Mathematical Modeling
  • High-Performance Programming

Honors & awards

  • Yale Domestic Summer Award

    May 2020

  • Runner Up

    Yale CBIT Healthcare Hackathon, January 2021

  • Tsai City Accelerator Program

    Yale Tsai Center for Innovative Thinking, November 2020

05 · Projects

Projects

Selected work across AI, proof complexity, scientific computing, tools, and games.

FIG. 03

GeneKnow

Genetic data never has to leave the machine.

A privacy-first, local-first genomic risk assessment platform. It processes genetic data entirely on your machine. Nothing leaves the device.

Tauri · Rust · React · TypeScript · LangGraph · Genomics · Privacy-First · Machine Learning

GeneKnow screenshot 1
GeneKnow screenshot 2
GeneKnow screenshot 3

FIG. 04

LAPACK AI

AlphaTensor inside LAPACK using Fortran and C.

An open-source implementation of the AlphaTensor 4x4 matrix multiplication algorithm in LAPACK: 49 operations, CPU optimizations, OpenCL GPU kernels on NVIDIA hardware, and real LAPACK integration.

Fortran · C/C++ · AI/ML · Linear Algebra · Scientific Computing · Performance Optimization

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FIG. 05

MarketSnap

Offline-first stock posts for vendors, before produce spoils.

Vendors share fresh-stock photos and short clips that work offline, sync when the signal comes back, and expire after 24 hours. Flutter, iOS and Android.

Flutter · Dart · Firebase · Mobile App · Cross-Platform · Real-time

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FIG. 06

FunnelFluent

Writing assistance for sales funnels.

A Next.js writing assistant for business proposals and marketing copy. Firebase, real-time collaboration, and AI suggestions. Grammarly, but for funnels.

Next.js · Firebase · TypeScript · React · AI/ML · Real-time Collaboration · Writing Assistant

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FIG. 07

Personyx

Interview evidence to be used during product development.

A desktop app that clusters customer interviews into personas, scores PRDs against that evidence, and lets you chat with persona bots while you work.

Electron · TypeScript · React · AI/ML · Desktop App · Product Management

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FIG. 08

Children of Singularity

A salvage sim inspired by Moebius, Planetes, and Nausicaä.

A 2.5D/3D multiplayer salvage sim. Explore cluttered orbital zones, trade debris, upgrade your ship, and slowly figure out what is running the place.

Godot · Game Development · Sci-fi · Multiplayer · GDScript · 2D/2.5D

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06 · Additional

Additional projects

Research, a medical device, a rocket, and protein interfaces.

09

Stochastic Computational Modeling of HIV

PLOS Computational Biology

A published model of noisy latent HIV activation.

A transcriptional cycling model of noisy inducible transcription and variable activation of quiescent HIV in T cells.

MATLAB · NFSim · R · Computational Biology

10

Simplifying Fracture Treatment: Medical Device Set

Yale School of Engineering and Applied Science

External fastening for Kirschner wires that otherwise migrate.

A device that externally fastens Kirschner wires so they stay at the fracture site instead of wandering into the body.

MATLAB · Python · CAD · Medical Device

11

Project Rocket: Yale Undergraduate Aerospace

YUAA · IREC

Hybrid propulsion for a national IREC rocket.

Designed and built hybrid solid-liquid fuel rockets for the national IREC competition, with a focus on propulsion and aerodynamics.

MATLAB · CAD · Aerospace Engineering · Propulsion

12

Bioinformatics of Protein-Protein Interactions

Oden Institute for Computational Engineering and Sciences

Protein interfaces and gene enrichment on TCGA data.

Visualized protein-protein interactions and ran gene enrichment analyses on TCGA high-throughput human data.

R · ChimeraX · Bioinformatics · TCGA Data

07 · Contact

Get in touch

Open to collaboration. Email is the fastest path.

Direct line

nmmsoftware@gmail.com

Send email